Cartilage cell transplantation to repair joint damage.
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Matrix-induced autologous chondrocyte implantation
Cartilage cell transplant to repair joint damage.
Detailed explanation: This advanced technique involves extracting healthy cartilage cells from the patient, growing them in a laboratory, and then implanting them into the damaged area of the knee. The cultured cells regenerate the cartilage and help restore joint function.
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Matrix-Induced Autologous Chondrocyte Implantation (MACI) is an FDA-approved procedure that uses a patient's own cells to repair cartilage defects in the knee. This procedure can help alleviate knee pain, restore function, and may prevent or delay arthritis.
Overview
Knee cartilage injuries, caused by repetitive actions or traumatic events, can lead to pain, swelling, and restricted movement. Cartilage has a poor blood supply, so it heals slowly. MACI may be an option when other treatments fail.
Ideal Candidate
This procedure is recommended for young patients with a single lesion under 2 centimeters and healthy underlying bone.
Procedure Steps
- Obtaining the Biopsy: A small biopsy of healthy cartilage is taken from a non-weight-bearing part of the knee.
- Biopsy Processing: The biopsy is sent to a facility where chondrocytes (cartilage-producing cells) are extracted and placed onto a layer of collagen.
- Chondrocyte Regeneration: The embedded chondrocytes regenerate within the collagen matrix to form implant tissue. This process takes about 6 weeks.
- MACI Delivery: The implant is then delivered to your surgeon for the procedure.